Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Abnormal uterine bleeding (AUB) is a common and concerning symptom in perimenopausal women, often requiring accurate differentiation between benign and malignant uterine lesions. This study aimed to compare the diagnostic performance of Transvaginal Sonography (TVS) and Magnetic Resonance Imaging (MRI) in the evaluation of uterine lesions in women with perimenopausal bleeding, with histopathological examination as the gold standard. This prospective observational study was conducted at Sree Mookambika Institute of Medical Sciences from June 2024 to December 2024. 50 patients with perimenopausal bleeding who underwent TVS, MRI, and subsequent histopathological confirmation were included. The diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of TVS and MRI were calculated and compared. MRI demonstrated superior diagnostic performance compared to TVS. The overall accuracy of MRI in characterizing uterine lesions was 97.09%, while that of TVS was 83.47%. For detecting malignant lesions, MRI showed a sensitivity of 99.98% and specificity of 95.76%, whereas TVS had a sensitivity of 62% and specificity of 95.25%. Diffusion-weighted imaging (DWI) on MRI achieved 100% sensitivity and specificity in differentiating benign from malignant lesions. MRI was particularly superior in detecting myometrial invasion, parametrial involvement, cervical extension, adnexal lesions, and lymph node metastases. MRI is a highly accurate and reliable imaging modality for the evaluation of uterine lesions in perimenopausal bleeding, outperforming TVS, especially in characterizing malignant lesions and assessing local extension. While TVS remains a useful initial screening tool due to its accessibility and low cost, MRI should be considered as a valuable problem-solving tool or primary imaging modality in sonographically indeterminate or suspicious cases to improve diagnostic precision and clinical decision-making.
How to cite this article:
Vinod Sukumaran, Dayaakar and Sathish Babu. Assessing the Diagnostic Performance of MRI in Perimenopausal Bleeding in Comparison with Transvaginal Sonography.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.1003.1007
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.1003.1007