Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
There are numerous tests to evaluate bone mineralization. The biochemical tests include serum vitamin D and parathyroid hormone (PTH)., markers of bone formation like osteocalcin, bone specific alkaline phosphates and serum carboxy terminal propeptide of type 1 collagen, and markers of bone resorption like plasma tartarate resistant acid phosphates, urinary deoxy‐pyridinolline cross linked telopeptide of type 1 collagen, deoxy‐pyridolline and urinary hydroxyproline. Children with asthma (diagnosed in accordance to GINA guidelines) in the age group of 7‐17 years who have been receiving high dose Budesonide ($400μg/day in 6‐11 years and $800μg/day in more than 11 years) for at least $2 years were enrolled as cases. The mean serum calcium level among the cases was found to be 9.2±0.6mg/dl against a normal reference range of 8.5‐10 mg/dL. All except one participant had normal serum levels of calcium. The mean serum vitamin‐D level was found to be 55.7±16.0nmol/L against a normal reference range of 40‐145nmol/L. Five patients were found to be vitamin‐D deficient. Vitamin‐D deficiency status was not found to be different in subjects with low BMD when compared to subjects with normal BMD. The mean serum PTH level was found to be 44.0±25.2 pg/mL against the reference range of 14‐75pg/ml. One subject was found to have high PTH level along with low vitamin‐D level.
How to cite this article:
H.C. Madhu, Sumanth H. Patil, N. Sowmya and G. Chaitra. Serum Calcium and Vit D in Children with Asthma on Long Term High Dose Inhaled Bedizened.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.367.370
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.367.370