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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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Study to Compare Epidural Bupivacaine with Buprenorphine and Bupivacaine with Fentanyl for Characteristics of Block and Prolongation of Postoperative Analgesia in Adult Orthopaedic Lower Limb Surgeries

Shilpa Khanapure, Sunita Y. Shende and Sarita R. Thanekar
Page: 493-500 | Received 20 Aug 2024, Published online: 05 Dec 2024

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https://doi.org/10.36478/makrjms.2024.12.493.500

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Abstract

Effective postoperative pain management is essential for enhanced recovery and reduced morbidity. Epidural anesthesia, combined with opioids, is a proven technique for intraoperative and postoperative analgesia. This study compares the efficacy and safety of Buprenorphine +Bupivacaine versus Fentanyl+Bupivacaine in elective lower limb orthopedic surgeries. A randomized study included 80 patients (ASA grade I‐II) undergoing lower limb surgeries. Group A received 3 mcg/kg buprenorphine+15ml of 0.5% bupivacaine and Group B received 50 mcg fentanyl+15ml of 0.5% bupivacaine. Onset and duration of sensory and motor blockade, analgesia duration, VAS scores and side effects were recorded. Sensory and Motor Blockade: Group A had a faster onset of sensory blockade (7.38±0.5 min) compared to Group B (9.15±0.6min., p<0.001). Sensory regression was significantly prolonged in Group A (269±10.5min) compared to Group B (246.2±8.2min., p<0.001). Postoperative Analgesia: Group A exhibited a longer duration of analgesia (535±20 min) compared to Group B (473.1±15.3min., p<0.001), while VAS scores favoured Group B at 6 and 24 hours. Side Effects: Group B had a slightly higher incidence of pruritus (10%) than Group A (7.5%), while nausea was more common in Group A. Buprenorphine+ Bupivacaine is superior for prolonged analgesia, while Fentanyl+Bupivacaine offers better immediate pain relief with fewer side effects. Both combinations are safe and effective for tailored patient care.

How to cite this article:

Shilpa Khanapure, Sunita Y. Shende and Sarita R. Thanekar. Study to Compare Epidural Bupivacaine with Buprenorphine and Bupivacaine with Fentanyl for Characteristics of Block and Prolongation of Postoperative Analgesia in Adult Orthopaedic Lower Limb Surgeries.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.493.500
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.493.500