Intrahepatic cholestasis of pregnancy is most common pregnancy related liver disorder and unique to pregnancy. It is characterised by pruritus with onset in the 2nd or 3rd trimester of pregnancy without skin rash, elevated serum amino transferases and bile acid levels and spontaneous relief of signs and symptoms within 2‐3 weeks after delivery. To find out the adverse effects of intrahepatic cholestasis of pregnancy on feto‐maternal outcomes. The present study was a prospective observational study. This Study was conducted from 1 ½ years (March 2018 to July 2019) at department of obstetrics and gynaecology in Chittaranjan Seva Sadan College of Obstetrics and Gynecology and Child Health. In 59.0% of the cases mode of delivery was Caesarean section which was significantly higher than that of VD (41.0%) (Z=2.54.,p=0.0107). Intrahepatic cholestasis of pregnancy is associated with elevated risks of preterm delivery, increased cesarean section rates and adverse neonatal outcomes. Effective management and timely delivery are crucial in minimizing these risks. Ongoing monitoring and interdisciplinary care are recommended to optimize both maternal and fetal health. Future research should explore strategies for better management and long‐term outcomes of women with ICP.
Nigar Anjum, Soma Basak and Saikat Kumar Sarkar. Feto‐Maternal Outcomes in Intrahepatic Cholestasis of Pregnancy.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.66.70
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.66.70