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Research Journal of Medical Sciences

ISSN: Online 1993-6095
ISSN: Print 1815-9346
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A Comparative Study of Orally Administered Nifedipine and Intravenously Administered Labetalol for Control of Blood Pressure in Hypertensive Emergencies of Pregnancy

A. Iqbal, R. Sharma, U. Ghosh, K.B. Sarkar and B.M. Rakshit
Page: 735-737 | Received 25 Sep 2024, Published online: 31 Dec 2024

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Abstract

Hypertensive disorders of pregnancy contribute significantly to maternal mortality worldwide. This study aimed to compare the effectiveness of orally administered Nifedipine and intravenously administered Labetalol in controlling blood pressure in hypertensive emergencies of pregnancy. A prospective, randomized controlled trial was conducted at a tertiary care hospital in West Bengal, India. Hundred pregnant women with hypertensive emergencies were randomly assigned to receive either oral Nifedipine or intravenous Labetalol. The primary outcome measure was the time taken to achieve target blood pressure. Secondary outcome measures included the number of doses required to achieve target blood pressure and maternal adverse effects. The results showed that both Nifedipine and Labetalol were effective in controlling blood pressure, but Nifedipine had a faster onset of action.


How to cite this article:

A. Iqbal, R. Sharma, U. Ghosh, K.B. Sarkar and B.M. Rakshit. A Comparative Study of Orally Administered Nifedipine and Intravenously Administered Labetalol for Control of Blood Pressure in Hypertensive Emergencies of Pregnancy.
DOI: https://doi.org/10.36478/10.36478/makrjms.2024.12.735.737
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makrjms.2024.12.735.737