Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Polypharmacy, or the use of multiple medications, is a major contributor to adverse drug reactions (ADRs). Although it carries potential risks, combining drugs can also provide significant benefits by alleviating symptoms, treating conditions, and preventing complications. However, with the growing availability of over‐the‐counter drugs and alternative medicines, maintaining a balance between the risks and benefits of polypharmacy has become increasingly challenging. This hospital‐based prospective observational study recorded patient data using a structured ADR reporting form. Information collected included baseline parameters, medical history, clinical findings, characteristics of ADRs, and details of both the suspected medications and those used for management. Data analysis was carried out using descriptive statistics with the Statistical Package for the Social Sciences (SPSS) version 25.0 software. During the study, 150 patients meeting the inclusion criteria were enrolled. Among them, 23 developed ADRs after admission. Polypharmacy was identified in 92 patients (61.4%), while 52 patients (38.6%) were not on polypharmacy, showing a statistically significant difference. Polypharmacy is a major contributor to adverse drug reactions (ADRs) due to drug–drug interactions, inappropriate prescribing, and cumulative side effects. Careful review of prescriptions, timely identification, and proper management of ADRs with regular monitoring are essential. Increasing awareness among healthcare professionals and educating patients can help minimize preventable ADRs.
How to cite this article:
Dr. K.N. Saivisveswar. Assessment of Adverse Drug Reactions in Patients Undergoing Polypharmacy in General Medicine Wards ‐ A Prospective Observational Study.
DOI: https://doi.org/10.36478/makrjms.2015.6.553.556
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2015.6.553.556