Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
Abstract
Upper gastrointestinal (UGI) symptoms are commonly encountered in clinical practice and often require endoscopic evaluation. Histopathological examination of biopsies obtained through oesophagogastroduodenoscopy (OGD scopy) plays a pivotal role in diagnosing a range of gastrointestinal disorders. To analyze and evaluate the histopathological patterns observed in UGI biopsies obtained via OGD scopy in patients presenting with gastrointestinal symptoms. This hospital‐based cross‐sectional descriptive study was conducted over 3 years at a tertiary care center in South India. A total of 520 biopsy specimens from the esophagus, stomach, and duodenum were analyzed histologically using hematoxylin and eosin (H&E) staining, with special stains applied as necessary. Patient demographics, clinical data, and biopsy sites were documented and statistically analyzed using SPSS version 26. Among the 520 patients, 55.8% were male and 44.2% were female, with the majority in the 41–60 age group. Most biopsies were from the stomach (59.6%), followed by the duodenum (20.8%) and esophagus (19.6%). The most common esophageal lesion was esophagitis (35.3%), while chronic gastritis (45.2%) and non‐specific duodenitis (46.3%) predominated in the stomach and duodenum, respectively. Malignant lesions included gastric adenocarcinoma (14.8%), esophageal squamous cell carcinoma (27.4%), and duodenal adenocarcinoma (7.4%). OGD scopy biopsies reveal a wide histopathological spectrum. Chronic gastritis, esophagitis, and duodenitis are common benign findings, while notable malignancies highlight the importance of routine biopsy and histological evaluation in improving diagnostic accuracy and patient outcomes.
How to cite this article:
Jayasree Geothe, Anisha Nazar and Lilarani Vijayaraghavan. Study of Histopathological Spectrum of Ogd Scopy Biopsies at a Teritary Care Centre.
DOI: https://doi.org/10.36478/makrjms.2024.11.832.836
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2024.11.832.836