Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Analysis of the Laboratory Profile of Liver Abscess in Patients Presenting to the Surgical Department at A Tertiary Care Centre: A Prospective Observational Study
M. Deepanraj, Pruthviraj , Channanna Chidamber Rao and R. Ragul Pradeep
Page: 971-976 | Received 17 Oct 2024, Published online: 30 Dec 2024
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Abstract
Liver abscess is a well‐known condition that is often caused by parasite origin (amoebic) in underdeveloped nations and pyogenic in affluent ones. The goal of this research was to assess the microbiological spectrum of liver abscess, its etiological reasons, the medication susceptibility pattern of the isolates from the liver abscess, and the illness outcome. From January 2023 to June 2024, a prospective cross‐sectional research was done in the Departments of General Surgery and Microbiology among at , PES institute of medical sciences and research at Andhra Pradesh patients diagnosed with a liver abscess in the Department of Surgery of a tertiary care hospital. The patients were told about the trial and given their informed permission. From January 2023 to June 2024 (18 months), 90 consecutive individuals with a liver abscess were investigated. USG guided aspiration was used to obtain the Pus specimen. The most common etiological aetiology of the liver abscess (71%) was amoebic liver abscess. The most prevalent causal organism of pyogenic liver abscess (11%) was E. coli. The bulk of the patients were middle‐aged guys with low socioeconomic position and were chronic drinkers. Fever (89%) and stomach discomfort (62%) were the most prevalent symptoms, with hepatomegaly (58%) being a common indicator. The research found complications such as abscess rupture (four instances), sepsis (four cases), chronic liver disease (two cases), and liver failure (two cases). The treatment approach in this research includes beginning patients on a first empirical antibiotic regimen. In addition, in the majority of instances, abscess drainage was performed using fine‐needle aspiration (42%), or pigtail drainage (27%). Only 11% of the cases were complex enough to need open surgery. Amoebic liver abscess is the most frequent kind of liver abscess in India, followed by pyogenic liver abscess. The most prevalent bacterium recovered from pyogenic abscesses is E.coli. The most prevalent pattern in our investigation was a solitary right lobe abscess. Early and adequate antibiotic therapy, as well as abscess drainage, have resulted in a better clinical outcome.
How to cite this article:
M. Deepanraj, Pruthviraj , Channanna Chidamber Rao and R. Ragul Pradeep. Analysis of the Laboratory Profile of Liver Abscess in Patients Presenting to the Surgical Department at A Tertiary Care Centre: A Prospective Observational Study.
DOI: https://doi.org/10.36478/makrjms.2024.12.971.976
URL: https://www.makhillpublications.co/view-article/1815-9346/makrjms.2024.12.971.976