Research Journal of Medical Sciences
ISSN: Online 1993-6095ISSN: Print 1815-9346
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Abstract
Scrub typhus is a common rickettsial infection of human caused by Orientia tsutsugamushi contracted through the bite of an infected mite. India is endemic for this disease and it is often found in pediatric population presented with fever, rash, hepatomegaly, edema, lymphadenopathy and eschar. But Scrub typhus is extremely rare in neonates and often we do not consider this diagnosis initially ,as the presentation is almost sepsis like . Here we reported a series of three cases of neonatal scrub typhus who presented with high grade unremitting fever with varying features of hepatosplenomegaly, convulsion, respiratory distress, oliguria, jaundice, while only one had eschar on chest. Laboratory investigations revealed thrombocytopenia, altered hepatic and renal function, CSF pleocytosis with negative sepsis screen and blood culture. They treated initially as sepsis, meningitis or pneumonia without much improvement. Then IgM scrub typhus report came positive and the neonates start recovering dramatically within few days of using doxycycline (in two cases) or azithromycin (in one case)with gradual normalization of clinical and laboratory parameters. So scrub typhus should be considered as a differential diagnosis in every sick neonates with persistent fever and other signs of sepsis, specially in endemic countries like India. Rarity of the neonatal scrub typhus presented as sepsis with multisystem involvement prompted us to report these cases.
How to cite this article:
Mukulika Maiti, Subhendu Dey, Mukut Banerjee, Tarak Nath Ghosh and Sumanta Laha. Neonatal Scrub Typhus Mimicking Sepsis with Multisystem Involvement : A Rare Case Series.
DOI: https://doi.org/10.36478/10.36478/makijtm.2024.3.144.147
URL: https://www.makhillpublications.co/view-article/1815-9346/10.36478/makijtm.2024.3.144.147