Nasal polyps are benign growths within the nasal passages, often associated with chronic inflammation. While various factors contribute to their development, the exact etiology remains unclear. Fungal infections have been linked to nasal polyposis, primarily in immunocompromised individuals. Here we present description of three cases where the same was found in immunocompetent individuals. This case series describes three immunocompetent individuals with severe nasal polyposis. A 40‐year‐old woman presented with a three‐year history of nasal blockage, frontal headache, and intermittent right‐sided nasal discharge. Microscopic examination and fungal culture of the resected polyp revealed a mixed infection with Bipolarissp and Alternariasp. A 19‐year‐old man presented with a six‐month history of left‐sided nasal blockage, facial pain and anosmia. Fungal culture identified Aspergillus niger in the resected polyp. A 65‐year‐old man presented with a nine‐month history of right‐sided nasal blockage and occasional bleeding. Fungal culture revealed Rhizopus species in the resected polyp. These cases demonstrate the importance of considering fungal infections in the etiology of nasal polyps, even in immunocompetent individuals. The presence of unusual fungal pathogens highlights the need for thorough microbiological investigations in patients with nasal polyposis, as this information can guide post‐surgical management and potentially improve patient outcomes.
Mousumi Paul, Tapan Majumder and Dipak Kumar Dhar. The Mycobiome of Nasal Polyps in Immunocompetent Individuals: A Case Series.
DOI: https://doi.org/10.36478/10.36478/makijtm.2025.1.76.81
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2025.1.76.81