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International Journal of Tropical Medicine

ISSN: Online 1818-779X
ISSN: Print 1816-3319
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Direction of Analysis and Antibiotic resistance of Lower Respiratory Tract Infections (LRTIs) : A Study at Tertiary Care Hospital in North India

Ankita Tripathi
Page: 153-157 | Received 15 Jan 2023, Published online: 24 Feb 2023

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Abstract

Pneumonia or lower respiratory tract infection is a prevalent issue in respiratory treatment. This study was conducted to determine the Analysis Direction and Antibiotic resistance of Lower Respiratory Tract Infections (LRTIs). This is a study conducted from March 2021 to October 2023 in the Department of Microbiology in a teaching hospital that provides special list care. A total of 610 samples were obtained from both hospitalised and non‐hospitalized individuals, of all age groups and both genders, who were provisionally diagnosed with lower respiratory tract infections. The samples consisted of 384 sputum, 54 bronchial wash, 107 endotracheal tube secretions, and 65 pleural fluid. Of the 610 samples analysed, 384 were sputum, 107 were endotracheal aspirates, 54 were bronchial wash and 65 were pleural fluid. The majority of the samples analysed, 442 (72.4%), were from inpatients, whereas 168 (27.5%) were from outpatients. Out of the samples analysed, 352 (57.7%) exhibited the growth of several types of bacteria. The table‐1 displays the distribution of the samples and their positivity. Culture‐negative cases were suspected to have a viral cause or be tuberculosis patients. Certain antibiotics have a decreased susceptibility, possibly as a result of widespread and improper usage, drug addiction, drug adulteration, microbial mutation, and inadequate infection control measures. Regular antimicrobial monitoring is necessary to keep the guidelines up to date for appropriate empirical and targeted antibiotic therapy. It is determined that gramme negative bacilli were the most prevalent isolates found in lower respiratory tract infections, with Klebsiella species being the most frequently identified. The presence of ESBLs, MBLs and MRSA‐producing bacteria in our investigation, although infrequent, is worrisome.


How to cite this article:

Ankita Tripathi. Direction of Analysis and Antibiotic resistance of Lower Respiratory Tract Infections (LRTIs) : A Study at Tertiary Care Hospital in North India.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.1.153.157
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.1.153.157