International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
The current study was conducted to determine the frequency of different circumstances related to low platelet count and to document the changes in megakaryocytes in different cases of thrombocytopenia. These cases were then submitted for bone marrow investigation for different reasons between March 2021 and December 2022. Slides of BMA (leishman stained) were obtained and examined. The medical information, blood tests and other important lab tests were also collected. The biopsy sample was preserved in a 10% buffered formaline solution overnight and then subjected to decalcification for 48‐72 hrs, depending on the hardness of the sample, using a 15% EDTA solution. The most frequent reason for seeking a bone marrow examination in patients of thrombocytopenia was Dimorphic anaemia (24 cases, 30%). The second most frequent reason was MDS (12 cases, 15%) which was similarly followed by acute lymphocytic leukaemia (ALL) and blast crisis of chronic myeloid leukaemia (CML). Additional research on the assessment of changes in megakaryocytes and their role in thrombocytopenia can enhance our understanding of the development of various blood disorders. Megakaryocytes, thrombocytopenia, blood disorders.
How to cite this article:
Rohini Srivastava. A Study on Association Between Peripheral Blood Thrombocytopenia and Bone Marrow Findings.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.1.158.161
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.1.158.161