International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
164
Views
16
Downloads
Abstract
The study is to compare the outcome of ISPAD (2018) and BSPED (2020) guidelines in the management of DKA in terms of duration of resolution of DKA and occurrence of therapy related complications. The study was Prospective Observational study conducted for total duration of 24 months. Out of 30 DKA patients 16 were managed on ISPAD Guidelines (group 1) and 14 were managed on BSPED guidelines (group 2). Mean duration of time taken for resolution of DKA in ISPAD group with reference to pH was 25.63 hrs and in BSPED group was 26.93 hrs. Mean duration of time taken for RBS to fall below 250 mg dL-1 in ISPAD group was 8.44 hrs while in BSPED group was 7.57 hrs. Mean duration of IV insulin therapy in ISPAD group was 25.94 hours while in BSPED group was 27.64 hrs. No significant differences were seen among the groups with respect to time taken for resolution of DKA, duration of insulin therapy, time taken for RBS to fall below 250 mg dL-1. Independent sample t test displayed no statistically significant difference in mean measured Na, Corrected Na and Chloride between ISPAD and BSPED guidelines at Admission, at 12 hrs and at resolution (p>0.05). Hypoglycemic episodes were observed more in BSPED group but the results were not statistically significant. Hypokalemia episodes were more with ISPAD regimen compared to BSPED regimen. In our study none of the patients developed cerebral edema. Hypokalemia episodes were seen more among the ISPAD group. Hypoglycemic episodes were more in BSPED group. Outcome is comparable in both groups.
How to cite this article:
Basavaraj M. Patil, Kumar Angadi, B. Aishwarya and Ratna Malipatil. Comparison of ISPAD and BSPED Guidelines in the Management of Diabetic Ketoacidosis in A
Tertiarycare in Children.
DOI: https://doi.org/10.36478/10.59218/makijtm.2023.43.48
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2023.43.48