International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
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Abstract
This study aimed to investigate the clinical characteristics, blood abnormalities, endoscopic findings, and long‐term outcomes of Plummer‐ Vinson syndrome (PVS) in patients from India. A retrospective descriptive cross‐sectional study was conducted on 50 patients diagnosed with PVS at Meenakshi Medical College and Research Institute, India, over a 4‐year period. The study included 50 patients, with a predominantly female population (male‐to‐female ratio: 1:4) and mean age ±SD of 42±3.24 years. The majority (90%) belonged to lower socioeconomic classes. Intermittent dysphagia was the main presenting symptom. Blood tests revealed severe iron deficiency anemia, with a median hemoglobin level of 6 g/dl. Esophageal webs were detected in 92% of patients. Treatment primarily involved dilatation procedures. While 74% of patients responded favorably to iron supplementation alone. Over a 4‐year followup, 4% of patients developed malignancy, and 2% needed repeat dilatation procedures. This study highlights the high prevalence of PVS in India, particularly among females from lower socioeconomic backgrounds. However, vigilant post‐treatment monitoring is crucial due to the risk of malignancy and potential need for repeat interventions.
How to cite this article:
Bhavishya Sundar, Somnath Verma, P. Padmanabhan and N. Dinakaran. Plummer‐Vinson Syndrome: A Single Centre Cross
Sectional Longitudinal Study from South India.
DOI: https://doi.org/10.36478/10.59218/makijtm.2024.1.120.124
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2024.1.120.124