International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
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A Retrospective Study on Changing Profiles of Resistance Pattern of Methicillin Resistant Staphylococcus Aureus Isolates in Patients Admitted at a Tertiary Care Hospital in Namakkal
K.K. Kavitha, L. Shiva Shankari, K. Senthilkumar and A. Dhanasekaran
Page: 136-141 | Received 10 Jan 2024, Published online: 03 Mar 2024
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Abstract
Methicillin‐resistant Staphylococcus aureus (MRSA) poses a significant challenge in healthcare settings due to its resistance to multiple antibiotics. Understanding the evolving resistance patterns of MRSA is crucial for effective infection control and treatment strategies. This retrospective study aims to investigate the changing resistance patterns of MRSA isolates in patients admitted to a tertiary care hospital in Namakkal, with a focus on the effectiveness of commonly used antibiotics and the impact of infection control measures on resistance trends. We analyzed the antibiotic resistance profiles of 160 MRSA isolates collected from patients admitted to the hospital between January 1, 2022 and December 31, 2023. Resistance patterns were assessed against a panel of antibiotics, including Ciprofloxacin, Vancomycin and Linezolid. Statistical analysis involved calculating odds ratios (OR), 95% confidence intervals (CI) and p‐values to evaluate the significance of resistance trends and the impact of infection control measures. The study revealed a high resistance rate to Ciprofloxacin (62.5%), while resistance rates to Vancomycin (12.5%) and Linezolid (18.75%) were significantly lower. Implementation of enhanced infection control and antibiotic stewardship programs demonstrated a reduction in MRSA resistance rates, underscoring the effectiveness of these interventions in controlling antibiotic resistance. The findings highlight the persistent challenge of MRSA and the need for continuous surveillance of resistance patterns. The study underscores the importance of judicious antibiotic use and robust infection control measures in managing MRSA infections and curbing the spread of resistance.
How to cite this article:
K.K. Kavitha, L. Shiva Shankari, K. Senthilkumar and A. Dhanasekaran. A Retrospective Study on Changing Profiles of Resistance Pattern of Methicillin Resistant Staphylococcus Aureus Isolates in Patients Admitted at a Tertiary Care Hospital in Namakkal.
DOI: https://doi.org/10.36478/10.59218/makijtm.2024.1.136.141
URL: https://www.makhillpublications.co/view-article/1816-3319/10.59218/makijtm.2024.1.136.141